Among more than 3,300 overweight or obese patients, those who took topiramate for at least four months lost 11.8 pounds more on average than individuals who took “dummy” pills, or placebo, found the meta-analysis, a systematic and quantitative review of published studies.
Can Topamax be taken long term?
To date, there are no known problems associated with long term use of topiramate. It is a safe and effective medication when used as directed.
Is it better to take Topamax in the morning or at night for weight loss?
At the start of treatment TOPAMAX may be taken once a day, preferably at night. After the dose is increased, it is taken twice a day. You should continue taking TOPAMAX until your doctor tells you to stop.
What happens when you stop taking Topamax?
Do not stop taking topiramate without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking topiramate, you may have severe seizures, even if you have not had seizures in the past. Your doctor will probably decrease your dose gradually.
Do you gain weight back after stopping Topamax?
Conclusions: Loss of body weight is a reversible effect, which at 6 months after TPM discontinuation shows a clear trend to return to baseline values. HOMA-IR is the only predictive factor of weight regain.
What does Topamax do to your brain?
Topiramate affects the activity of two neurotransmitters in the brain. Neurotransmitters are natural chemicals that are involved in transmitting messages between the nerve cells. Topiramate enhances the action of GABA, which is a neurotransmitter that acts as a natural ‘nerve calming’ agent.
How long can you stay on Topamax?
Since Topamax can stay in your system for up to six days, women should be aware that the medication reduces the effectiveness of birth control, so they need to take further precautions against pregnancy.
How do you feel on Topamax?
What are the side effects of Topamax?
- tingling of the arms and legs (paresthesia)
- not feeling hungry.
- weight loss.
- speech problems.
- dizziness or sleepiness.
- slow reactions (psychomotor slowing)
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How much weight will you lose on Topamax?
For oral dosage form (extended-release capsules): For weight loss: Adults—At first, one tablet of 3.75 milligrams (mg) of phentermine and 23 mg of topiramate once a day for 14 days. After 14 days, your doctor may increase your dose to 7.5 mg of phentermine and 46 mg of topiramate once a day.
How much weight can you lose with topiramate?
All patients lost a substantial amount of weight on topiramate. The average weight loss was 22 lb (10 kg; range, 8–56 lb [4–25 kg]).
Is topiramate 50mg used for weight loss?
Recent reports have shown that the anticonvulsant topiramate causes weight loss in various patient groups. The drug has also shown effectiveness in open trials as a mood stabilizer in patients with affective disorders, but not in controlled trials in the acute treatment of mania.
Do I need to wean off Topamax?
6) Topiramate (Topamax)
Taken for epilepsy, migraine headache prevention, weight loss (as one of the active ingredients in Qsymia) and alcohol abuse disorder, topiramate should not be abruptly discontinued. Instead, taper your dosage gradually over 2 to 8 weeks to prevent rebound effects.
Will I lose weight on Topamax?
Summary: The drug topiramate can help people lose weight as long as they can tolerate the side effects, according to authors of a new study that reviewed the medical literature, according to Brazilian researchers.
Does Topamax cause permanent memory loss?
Can Topamax cause permanent memory loss? Topamax may be associated with dementia and should be used with caution in older patients. Still, it has not been well established that Topamax can cause permanent memory loss.
Does Topamax slow down metabolism?
Topiramate reduced food intake acutely and increased metabolic rate. There were also significant reductions in leptin, insulin, and corticosterone.
Can you gain weight on Topamax?
This meta-analysis found that topiramate was associated with weight loss or attenuated weight gain when compared to controls (−2.83 kg; 95% CI, −4.62 to −1.03).